PICO 10 - Interventions to optimize the chronic viral hepatitis care continuum: a systematic review and meta- analysis of interventions to improve hepatitis B and C screening, linkage to care, treatment uptake, treatment adherence, and viral suppression
نویسنده
چکیده
s screened (n = 469) Abstracts excluded (n = 353) Wrong methodology (119) Review article, editorial, or no results (107) Wrong outcome (97) Wrong population (30) Full-text articles assessed for eligibility (n = 116) Full-text articles excluded (n = 62) No control (17) Missing necessary data/results (12) Duplicate abstract of publication (9) Non-English language (7) National-level campaign (4) Only identifies risk factors/associations (4) Outcome not along cascade (3) No intervention (2) Only describes state of hepatitis management (2) Dissertation/thesis (2) Studies included in qualitative synthesis (n = 54) Full-text publication (45) Abstracts (5) Clinical trial (4) Studies included in quantitative synthesis (meta-analysis) (n = 31) Studies excluded from quantitative synthesis because of unique outcomes or intervention types (n = 23)
منابع مشابه
Evaluation of the need for treatment on 72 subjects with anti-HBe positive chronic hepatitis B
Background: Viral load and alanine aminotransferase (ALT) levels may not be the key points for making a decision in the treatment of anti-HBe positive chronic hepatitis B. The purpose of this study was to assess the histological evaluation of liver to find the need for treatment on 72 patients with anti-HBe positive chronic hepatitis B. Methods: The liver biopsy slides of the 72 patients (56 s...
متن کاملGut Microbiota and Chronic Hepatitis B and C Viruses-Induced Cirrhosis
Hepatitis B and C viruses are major public health problems. These viruses can chronically lead to liver disease such as fibrosis, cirrhosis, and hepatocellular carcinoma, which often increase mortality in these patients. According to previous studies, the liver is highly affected by changes in the microbiota of gastrointestinal tract and immune system damage caused by inflammation due to viral ...
متن کاملDetection of Pre-treatment mutations leading to resistance to direct hepatitis C virus blocking drugs in patients with chronic hepatitis C
Background and objective: Human is the only host of hepatitis C virus. This virus has a positive single stranded RNA and lipoprotein envelop that has 7 confirmed genotypes. According to studies, genotypes 1a, 3a and 1b are the most common genotypes in Iran. No effective vaccine against HCV infection has been developed instead, advances in antiviral treatment using drugs that directly affect spe...
متن کاملBuilding the evidence base to eliminate hepatitis B and C as public health threats.
www.thelancet.com/infection Published online September 5, 2016 http://dx.doi.org/10.1016/S1473-3099(16)30272-9 1 The rigorous analysis of evidence by Kali Zhou and colleagues is a benchmark endeavour that reveals both the evidence-based interventions that improve hepatitis B virus (HBV) and hepatitis C virus (HCV) testing and linkage to care and treatment (ie, the care cascade), and the major r...
متن کاملDistribution of Genotypes of B and C Hepatitis Viruses in Guilan Province
Today, chronic viral hepatitis is considered as a public health problem in the world. Totally, 5% of the world population, especially in Asia and Africa suffer from this problem. The prevalence of acute hepatitis in America is 0.1-0.2 percent, 50% of those with hepatitis C (HCV) and 5-10% of them with hepatitis B (HCV) develop chronic hepatitis. Determining HBV and HCV genotypes is important to...
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تاریخ انتشار 2017